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Gelsolin (GSN) Peptide

GSN Reactivité: Humain Hôte: Synthetic BP, WB, IHC
N° du produit ABIN977721

Aperçu rapide pour Gelsolin (GSN) Peptide (ABIN977721)

Antigène

Gelsolin (GSN)

Origine

Humain

Source

  • 6
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-GSN antibody (Catalog #: ARP54299_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    Gelsolin (GSN)

    Sujet

    GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. It is a calcium-regulated protein, which functions in both assembly and disassembly of actin filaments. Defects in the gene encoding GSN are a cause of familial amyloidosis Finnish type (FAF).The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

    Alias Symbols: DKFZp313L0718, ADF, AGEL

    Protein Interaction Partner: tax,ACTA1,ACTB,ACTG1,ACTN4,APP,AR,BCAR1,CASP3,CLIC5,CSK,FHIT,FN1,LIMK2,PIK3CG,PTK2B,PXN,TNIK,TOM1L1,VASP,VCL,VDAC1,ACTA1,ACTN4,APP,AR,CASP4,FN1,PIK3CA,PLCG1,PPM1B,PTK2,PTK2B,PTPN12,PXN,SRC,STK39,TOM1L1,VCL,VDAC1

    Protein Size: 782

    Poids moléculaire

    83 kDa

    ID gène

    2934

    NCBI Accession

    NM_000177, NP_000168

    UniProt

    P06396
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